Introducing: Integrated Myocardial Flow Reserve (iMFR)
iMFR is a validated new metric that builds upon Myocardial Flow Reserve (MFR). iMFR combines two key cardiac quantification techniques:
- Relative Stress Perfusion: Measures tracer uptake distribution within the myocardium to detect perfusion abnormalities.
- Myocardial Flow Reserve (MFR): The ratio of absolute myocardial blood flow (MBF) during stress to MBF at rest, assessing flow capability in both normal and impaired regions.
By merging these metrics, iMFR classifies myocardial perfusion as normal, focally impaired, or diffusely impaired.
iMFR improves understanding of disease burden. Its diagnostic and prognostic value has been validated in studies of over 1,000 patients. Risk maps generated in 4DM help identify:
- Focally impaired perfusion—a predictor of obstructive CAD.
- Diffusely impaired perfusion—an independent marker of mortality risk.
