Venkatesh Murthy, Judson Jones, Jeffery Meden, Edward Ficaro and James Corbett
University of Michigan Health System, Ann Arbor, MI. Journal of Nuclear Medicine, 2013; 54 (Suppl 2):351.
Description:
This study evaluated whether Regadenoson-induced pharmacologic stress increases the amplitude of respiratory motion during Rb-82 PET myocardial perfusion imaging (MPI). Using a novel quantitative tracking method that measured tracer displacement over time, respiratory motion at rest and during Regadenoson stress was compared in 53 subjects (46 patients and 7 volunteers).
Clinical Relevance:
Despite Regadenoson’s association with dyspnea, this study demonstrated that respiratory motion amplitude does not meaningfully increase during stress PET imaging. These findings suggest that image quality and motion-related artifacts remain stable under Regadenoson stress, supporting its continued reliability for high-quality MPI acquisitions.
Partners in Research:
INVIA Medical Imaging Solutions and the University of Michigan collaborated on this research.
