EP Ficaro, JN Kritzman, JR Corbett
University of Michigan Health System, Ann Arbor, MI. Presented at the 8th Annual ASNC Scientific Session, Indianapolis, 2003.
Description:
This study investigated how basal plane motion impacts left ventricular ejection fraction (LVEF) estimates derived from gated myocardial perfusion SPECT, and explored methods to improve agreement between two widely used quantitative analysis programs, 4D-MSPECT (4DM) and Cedars QGS. Differences in how these software packages model basal motion between end-diastole (ED) and end-systole (ES) can influence calculated LVEF values, potentially complicating serial or comparative assessments.
Clinical Relevance:
Constraining the basal motion to 0 to 6mm minimizes differences between QGS and 4DM, allowing more consistent serial LVEF assessments. However, accuracy is compromised as seen from a comparison to the CVG values (CVG=52%, 4DM=51%, QGS=47%).
