VJ.N. Kritzman, E.P. Ficaro, J.R. Corbett
University of Michigan Health System, Ann Arbor, MI. Journal of Nuclear Medicine, 2001; 42(5):50P.
Description:
This study evaluated how imaging protocol, gender, and attenuation correction (AC) influence quantitatively measured post-stress left ventricular (LV) volume ratios in myocardial perfusion SPECT imaging. The goal was to establish normal ranges for LV stress/rest volume ratios under different imaging and correction conditions.
Clinical Relevance:
Understanding normal variability in post-stress LV dilation is essential for distinguishing physiologic changes from pathologic dilation. This work defined reliable normal limits for quantitative LV volume ratios, demonstrating that gender and attenuation correction do not affect normal ranges, while imaging protocol exerts a modest but statistically significant influence.
Partners in Research:
INVIA Medical Imaging Solutions and the University of Michigan collaborated on this research.