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Description:
This review highlights the impact of recent technological improvements on MBF quantification and technical considerations that remain important for clinical applications.
Clinical Relevance:
Accurate quantification of MBF and MFR can bolster diagnostic capabilities and potentially transform patient care. This is particularly crucial given the current variability in scanner performance, which ranges from high-end PET/CT systems to older generation scanners with inherent limitations. By aiming for standardization akin to the oncological PET community’s efforts with SUV quantification of FDG PET, the field can achieve more consistent and reliable clinical outcomes. Robust understanding and mitigation of methodological errors will likely widen the acceptance of stress-only blood flow measurement, thereby optimizing the clinical application of these advanced quantification tools in everyday practice.
Partners in Research:
INVIA Medical Imaging Solutions and the University of Michigan collaborated on this research.
